Artificial Organs: We’re Entering an Era Where Transplants Are Obsolete

HELP ENLIGHTEN YOUR FELLOWS. BE SURE TO PASS THIS ON. SURVIVAL DEPENDS ON IT.

by Dom Galeon on December 4, 2017
Writing for FUTURISM

No More Heart Transplants

Around the world, lists of patients in need of an organ transplant are often longer than the lists of those willing (and able) to donate — in part because some of the most in-demand organs for transplant can only be donated after a person has died. By way of example, recent data from the British Heart Foundation (BHF) showed that the number of patients waiting for a heart transplant in the United Kingdom has grown by 162 percent in the last ten years.

Now, 50 years after the first successful heart transplant, experts believe we may be nearing an era where organ transplantation will no longer be necessary. “I think within ten years we won’t see any more heart transplants, except for people with congenital heart damage, where only a new heart will do,” Stephen Westaby, from the John Radcliffe Hospital in Oxford, told The Telegraph.

Westaby didn’t want to seem ungrateful for all the human lives saved by organ transplants, of course. On the contrary, he said that he’s a “great supporter of cardiac transplantation.” However, recent technological developments in medicine may well offer alternatives that could save more time, money, and lives.

“I think the combination of heart pumps and stem cells has the potential to be a good alternative which could help far more people,” Westaby told The Telegraph.

An Era of Artificial Organs

South African heart transplant pioneer Dr. Christiaan Barnard. Overnight he became a superstar.

Foremost among these medical advances, and one that while controversial has continued to demonstrate potential, is the use of stem cells. Granted, applications for stem cells are somewhat limited, though that’s down more to ethical considerations more than scientific limitations. Still, the studies that have been done with stem cells have proven that it is possible to grow organs in a lab, which could then be implanted.

Science has also made it possible to produce artificial organs using another technological marvel, 3D printing. When applied to medicine, the technique is referred to as 3D bioprinting — and the achievements in the emerging technique have already been quite remarkable.

Thus far, scientists have successfully 3D-bioprinted several organs, including  a thyroid gland, a tibia replacement that’s already been implanted into a patient, as well as a patch of heart cells that actually beat. All of these organs were made possible by refinements to the type of bioink; one of many improvements to the process we can expect to see in the years to come, as there’s now an institution dedicated to advancing 3D bioprinting techniques.


Other technologies that are making it possible to produce synthetic organs include a method for growing bioartificial kidneys, the result of a study in 2016.

For his part, Westaby is involved in several projects working to continue improving the process: one uses stem cells to reverse the scarring of heart tissue, which could improve the quality of life for patients undergoing coronary bypass. Westaby is also working on developing better hardware for these types of surgical procedures, including inexpensive titanium mechanical heart pumps.

Together with 3D bioprinting such innovations could well become the answer to donor shortages. The future of regenerative medicine is synthetic organs that could easily, affordably, and reliably be printed for patients on demand.


ABOUT THE AUTHOR
Dom Galeon is a writer with Futurism. Interests include history, science, philosophy, and film.

DOM GALEON—Thus far, scientists have successfully 3D-bioprinted several organs, including  a thyroid gland, a tibia replacement that’s already been implanted into a patient, as well as a patch of heart cells that actually beat. All of these organs were made possible by refinements to the type of bioink; one of many improvements to the process we can expect to see in the years to come, as there’s now an institution dedicated to advancing 3D bioprinting techniques.

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License

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The Best Definition of Donald Trump We Have Found

In his zeal to prove to his antagonists in the War Party that he is as bloodthirsty as their champion, Hillary Clinton, and more manly than Barack Obama, Trump seems to have gone “play-crazy” -- acting like an unpredictable maniac in order to terrorize the Russians into forcing some kind of dramatic concessions from their Syrian allies, or risk Armageddon.However, the “play-crazy” gambit can only work when the leader is, in real life, a disciplined and intelligent actor, who knows precisely what actual boundaries must not be crossed. That ain’t Donald Trump -- a pitifully shallow and ill-disciplined man, emotionally handicapped by obscene privilege and cognitively crippled by white American chauvinism. By pushing Trump into a corner and demanding that he display his most bellicose self, or be ceaselessly mocked as a “puppet” and minion of Russia, a lesser power, the War Party and its media and clandestine services have created a perfect storm of mayhem that may consume us all. Glen Ford, Editor in Chief, Black Agenda Report

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The Singularity Mystery—we may get to know the answer if we survive

FRONTLINENEWSLOGO-2


By Natalie Wolchover | LiveScience } Originally posted on September 10, 2012

What Is the Future of Computers?

Integrated circuit from an EPROM memory microchip showing the memory blocks and supporting circuitry. Credit: Creative Commons Attribution-Share Alike 3.0 Unported | Zephyris


In 1958, a Texas Instruments engineer named Jack Kilby cast a pattern onto the surface of an 11-millimeter-long “chip” of semiconducting germanium, creating the first ever integrated circuit. Because the circuit contained a single transistor — a sort of miniature switch — the chip could hold one “bit” of data: either a 1 or a 0, depending on the transistor’s configuration.

Since then, and with unflagging consistency, engineers have managed to double the number of transistors they can fit on computer chips every two years. They do it by regularly halving the size of transistors. Today, after dozens of iterations of this doubling and halving rule, transistors measure just a few atoms across, and a typical computer chip holds 9 million of them per square millimeter. Computers with more transistors can perform more computations per second (because there are more transistors available for firing), and are therefore more powerful. The doubling of computing power every two years is known as “Moore’s law,” after Gordon Moore, the Intel engineer who first noticed the trend in 1965.

Moore’s law renders last year’s laptop models defunct, and it will undoubtedly make next year’s tech devices breathtakingly small and fast compared to today’s. But consumerism aside, where is the exponential growth in computing power ultimately headed? Will computers eventually outsmart humans? And will they ever stop becoming more powerful?


The singularity

Many scientists believe the exponential growth in computing power leads inevitably to a future moment when computers will attain human-level intelligence: an event known as the “singularity.” And according to some, the time is nigh.

Physicist, author and self-described “futurist” Ray Kurzweil has predicted that computers will come to par with humans within two decades. He told Time Magazine last year that engineers will successfully reverse-engineer the human brain by the mid-2020s, and by the end of that decade, computers will be capable of human-level intelligence.

The conclusion follows from projecting Moore’s law into the future. If the doubling of computing power every two years continues to hold, “then by 2030 whatever technology we’re using will be sufficiently small that we can fit all the computing power that’s in a human brain into a physical volume the size of a brain,” explained Peter Denning, distinguished professor of computer science at the Naval Postgraduate School and an expert on innovation in computing. “Futurists believe that’s what you need for artificial intelligence. At that point, the computer starts thinking for itself.” [How to Build a Human Brain]

What happens next is uncertain — and has been the subject of speculation since the dawn of computing.

“Once the machine thinking method has started, it would not take long to outstrip our feeble powers,” Alan Turing said in 1951 at a talk entitled “Intelligent Machinery: A heretical theory,” presented at the University of Manchester in the United Kingdom. “At some stage therefore we should have to expect the machines to take control.” The British mathematician I.J. Good hypothesized that “ultraintelligent” machines, once created, could design even better machines. “There would then unquestionably be an ‘intelligence explosion,’ and the intelligence of man would be left far behind. Thus the first ultraintelligent machine is the last invention that man need ever make,” he wrote.

Buzz about the coming singularity has escalated to such a pitch that there’s even a book coming out next month, called “Singularity Rising” (BenBella Books), by James Miller, an associate professor of economics at Smith College, about how to survive in a post-singularity world. [Could the Internet Ever Be Destroyed?]


Brain-like processing

But not everyone puts stock in this notion of a singularity, or thinks we’ll ever reach it. “A lot of brain scientists now believe the complexity of the brain is so vast that even if we could build a computer that mimics the structure, we still don’t know if the thing we build would be able to function as a brain,” Denning told Life’s Little Mysteries. Perhaps without sensory inputs from the outside world, computers could never become self-aware.

Others argue that Moore’s law will soon start to break down, or that it has already. The argument stems from the fact that engineers can’t miniaturize transistors much more than they already have, because they’re already pushing atomic limits. “When there are only a few atoms in a transistor, you can no longer guarantee that a few atoms behave as they’re supposed to,” Denning explained. On the atomic scale, bizarre quantum effects set in. Transistors no longer maintain a single state represented by a “1” or a “0,” but instead vacillate unpredictably between the two states, rendering circuits and data storage unreliable. The other limiting factor, Denning says, is that transistors give off heat when they switch between states, and when too many transistors, regardless of their size, are crammed together onto a single silicon chip, the heat they collectively emit melts the chip.

For these reasons, some scientists say computing power is approaching its zenith. “Already we see a slowing down of Moore’s law,” the theoretical physicist Michio Kaku said in a BigThink lecture in May.

But if that’s the case, it’s news to many. Doyne Farmer, a professor of mathematics at Oxford University who studies the evolution of technology, says there is little evidence for an end to Moore’s law. “I am willing to bet that there is insufficient data to draw a conclusion that a slowing down [of Moore’s law] has been observed,” Farmer told Life’s Little Mysteries. He says computers continue to grow more powerful as they become more brain-like.

Computers can already perform individual operations orders of magnitude faster than humans can, Farmer said; meanwhile, the human brain remains far superior at parallel processing, or performing multiple operations at once. For most of the past half-century, engineers made computers faster by increasing the number of transistors in their processors, but they only recently began “parallelizing” computer processors. To work around the fact that individual processors can’t be packed with extra transistors, engineers have begun upping computing power by building multi-core processors, or systems of chips that perform calculations in parallel.”This controls the heat problem, because you can slow down the clock,” Denning explained. “Imagine that every time the processor’s clock ticks, the transistors fire. So instead of trying to speed up the clock to run all these transistors at faster rates, you can keep the clock slow and have parallel activity on all the chips.” He says Moore’s law will probably continue because the number of cores in computer processors will go on doubling every two years.

And because parallelization is the key to complexity, “In a sense multi-core processors make computers work more like the brain,” Farmer told Life’s Little Mysteries.

And then there’s the future possibility of quantum computing, a relatively new field that attempts to harness the uncertainty inherent in quantum states in order to perform vastly more complex calculations than are feasible with today’s computers. Whereas conventional computers store information in bits, quantum computers store information in qubits: particles, such as atoms or photons, whose states are “entangled” with one another, so that a change to one of the particles affects the states of all the others. Through entanglement, a single operation performed on a quantum computer theoretically allows the instantaneous performance of an inconceivably huge number of calculations, and each additional particle added to the system of entangled particles doubles the performance capabilities of the computer.

If physicists manage to harness the potential of quantum computers — something they are struggling to do — Moore’s law will certainly hold far into the future, they say.


Ultimate limit

If Moore’s law does hold, and computer power continues to rise exponentially (either through human ingenuity or under its own ultraintelligent steam), is there a point when the progress will be forced to stop? Physicists Lawrence Krauss and Glenn Starkman say “yes.” In 2005, they calculated that Moore’s law can only hold so long before computers actually run out of matter and energy in the universe to use as bits. Ultimately, computers will not be able to expand further; they will not be able to co-opt enough material to double their number of bits every two years, because the universe will be accelerating apart too fast for them to catch up and encompass more of it.

So, if Moore’s law continues to hold as accurately as it has so far, when do Krauss and Starkman say computers must stop growing? Projections indicate that computer will encompass the entire reachable universe, turning every bit of matter and energy into a part of its circuit, in 600 years’ time.

That might seem very soon. “Nevertheless, Moore’s law is an exponential law,” Starkman, a physicist at Case Western University, told Life’s Little Mysteries. You can only double the number of bits so many times before you require the entire universe.

Personally, Starkman thinks Moore’s law will break down long before the ultimate computer eats the universe. In fact, he thinks computers will stop getting more powerful in about 30 years. Ultimately, there’s no telling what will happen. We might reach the singularity — the point when computers become conscious, take over, and then start to self-improve. Or maybe we won’t. This month, Denning has a new paper out in the journal Communications of the ACM, called “Don’t feel bad if you can’t predict the future.” It’s about all the people who have tried to do so in the past, and failed.


This story was provided by Life’s Little Mysteries, a sister site to LiveScience. Follow Natalie Wolchover on Twitter @nattyover or Life’s Little Mysteries @llmysteries. We’re also on Facebook & Google+.



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All about singularity

singularity-robot

PATRICE GREANVILLE

SINGULARITY is one of those strange-sounding things that “normal” people usually neither understand nor fear, since they ascribe it to the kind of preoccupation typical of geeks. The fact, however, is that singularity is both a very exciting and awesome phenomenon, one likely to change our species forever. Most thinkers now predict this event to happen in less than one generation. (Assuming, of course, we survive the moral bankruptcy exhibited by our prostituted leaders.) In any case, learn a bit about this fascinating event, likely to alter our reality in ways that none of us ever expected. 

Published on May 3, 2016

Michio Kaku and Ray Kurzweil explains the exponential rate at which Technological Singularity is approaching and the future is far near than we can Imagine!

2029 : Singularity Year – Neil deGrasse Tyson & Ray Kurzweil – https://www.youtube.com/watch?v=EyFYF…

Life Changing Future Technologies [Full Documentary] :https://www.youtube.com/watch?v=TRSlk…

The technological singularity is a hypothetical event in which artificial general intelligence (constituting, for example, intelligent computers, computer networks, or robots) would be capable of recursive self-improvement (progressively redesigning itself), or of autonomously building ever smarter and more powerful machines than itself, up to the point of a runaway effect—an intelligence explosion—that yields an intelligence surpassing all current human control or understanding. Because the capabilities of such a superintelligence may be impossible for a human to comprehend, the technological singularity is the point beyond which events may become unpredictable or even unfathomable to human intelligence.




Washington Fraud and Geopolitics: Excluding Russia from the Olympics

=By=
Peter Koenig


Why doesn’t the world just leave the entire Olympics to the Masters of the Universe, the United States of America?

olympics

The Unites States, once more, under false pretenses is attempting – and possibly succeeding – in punishing, or in Washington’s jargon, ‘sanctioning’ Russia for allegedly having systematized doping during the 2014 Sochi Olympics. They know no scruples, these masters of lies and manipulations in Washington. Fortunately, they are becoming more and more careless and flagrant in what they are doing – so that increasingly people will become aware of the criminal nature of the Washington government and its European vassals which support whatever atrocities the US is inflicting – or attempting to inflict – on the world.

russianAthletes-putin

In this case Washington already enlisted their vassal Canada to write to the International Olympic Committee (IOC) in Lausanne, Switzerland, requesting exclusion of Russia from the 2016 Olympics in Rio. They are doing the same with European vassals – asking them to put pressure on the IOC.

In the meantime, they – the criminals of Washington – bought already the International Association of Athletics Federations (IAAF) to exclude Russia’s 68 track and field athletes, without any evidence that they were ever involved in doping. There exists literally no international organization on this globe that is not bought or blackmailed or simply prostituted into following the dictate of the evil empire.

What a shame for the world, for us, the People… that we allow this aberration of all morals and ethics – and let it become the new norms, the new normal – same as state assassinations, false flags – in the name of the empire, to further its objectives of Full Spectrum World Dominance…

What a shame for the world, for us, the People, that we allow this aberration of all morals and ethics – and let it become the new norms, the new normal – same as state assassinations, false flags – in the name of the empire, to further its objectives of Full Spectrum World Dominance – and in this case, being as usual The Greatest, also in sports, with a widely reduced competition.

Washington has falsely and without evidence accused the Russian Minister of Sports, Vitali Mutkó, of having been the orchestrator of the ‘Russian drug scandal’ (sic) in Sochi. Mr. Mutkó rightly reacted calling the allegation a farce, ‘a civil commission is accusing a nation’.

[dropcap]O[/dropcap]f course, nobody dares talk about the US doping scandals, the real scandals. For example, Lance Armstrong won the French cycling contest, La Tour de France, seven consecutive times from 1999 to 2005. He also won the bronze medal in the 2000 Summer Olympics in Sydney. In 2012 the US Anti-Doping Agency (ADA) found that he had taken performance enhancing drugs throughout his career. The ADA named him the ringleader of “the most sophisticated, professionalized and successful doping program that sport has ever seen”.

Furthermore, Internet offers an incomplete list of 235 US sports people, who have been involved in ‘drug cases’

Has this been a reason for Russia to start a sports war of aggression against the US? – Of course not. The aggressor is always the same – the emperor, limping on his last leg. Well, why doesn’t the world leave the entire Olympics to the Masters of the Universe, the United States of America?

Please allow me to call on the entire world, or at least on those who dare to call themselves free and unaligned countries, to boycott the coming Rio Olympics in solidarity with Russia.

Sorry for Brazil, but in fact, even Brazil may join, as an unaligned nation – as the current ultra-corrupt interim government of Michel Kemer – put there in an illegal coup – guess by whom? – is not a legitimate representative of Brazil.

Russia, China and the Eurasian countries really don’t need to compete against the constantly treacherous west. They may at any time organize and invite to the New Eastern Olympics, with anybody being welcome to participate and perform – even the Masters of the Universe.

This is in any case the new direction he world is about to take. Looking East. That’s where the future lays. A dawning future, as the sunrise indicates, a future of peace and prosperity, sports included.


About the author
Peter Koenig is an economist and geopolitical analyst. He is also a former World Bank staff and worked extensively around the world in the fields of environment and water resources. He writes regularly for Global Research, ICH, RT, Sputnik, PressTV, Chinese 4th Media, TeleSUR, The Vineyard of The Saker Blog, and other internet sites. He is the author of Implosion – An Economic Thriller about War, Environmental Destruction and Corporate Greed – fiction based on facts and on 30 years of World Bank experience around the globe. He is also a co-author of The World Order and Revolution! – Essays from the Resistance. 

This is a simulpost with Global Research, a fraternal organization.

 

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Here’s what it actually means to die ‘of old age’


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HBO/Game of Thrones

Ever ask someone how their family member passed away and hear them say they simply “died of old age”?

As it turns out, that’s almost never quite what’s going on from a medical perspective. Aging – in and of itself – is not a cause of death. (There is a phenomenon known as “geriatric failure to thrive,” which scientists are studying, but it’s extremely rare.)

When most of us say that someone died of old age, what we really mean is that someone died as a result of an illness (like pneumonia) or as a result of an event (like a heart attack) that a healthy, stronger person would likely have survived.

These are often quiet deaths, like what happens when an older person’s “heart just stops in their sleep.” This usually means that the person had a heart attack in the middle of the night. Another example is if someone “had a bad fall, and it was just downhill from there.” The person likely broke a hip, survived surgery, but then got pneumonia in the hospital and died from the infection.

Most often, what claims the lives of older people is actually an accumulation of things.

“As you get older and older, you’re more likely to get heart disease and cancer,” Amy Ehrlich, a professor of clinical medicine at the Albert Einstein College of Medicine and a geriatric physician at Montefiore Medical Center, told Business Insider last year. “But we also see a lot of things like falls, where someone falls and ends up with serious trauma like a hip fracture. That’s hard to recover from when you’re 104.”

This presents us with a new question:

If we don’t die as a result of aging, then what the heck is aging?

melisandre game of thrones

“Game of Thrones” character Melisandre (“the Red Woman”) doesn’t appear to age, thanks to magic. HBO

Humans didn’t always live long enough to age. We used to die long before our skin began to sag or our muscles began to wither, succumbing instead to diseases for which we now have vaccines, like tuberculosis or smallpox, or we died from gastrointestinal infections, which can cause diarrhea.

Somewhere around the 1950s (at least in America and other wealthy countries), we started living nearly twice as long as our ancestors had just a century before. We now spend a massive portion (nearly half!) of our lives getting old before we die.

What if it didn’t have to be like this?

What if we experienced aging and then came out of it – or didn’t age at all? That’s how some animals do it.

2014 study comparing the mortality rates of 46 different species found that some organisms don’t age – their mortality rates stay constant from around the time they’re born until around the time they die. Others enter a period of aging (like the kind most of us experience around age 65) and then come out of it, continuing their lives.

Here’s a chart from that study showing what aging looks like in a modern-day human. (Mortality rates are in red, fertility rates in blue.)

aging_1Nature

See that sharp rise in the thin red line? We have an incredibly long aging period.

But lots of other creatures’ life spans look nothing like this. Take a look, for example, at the “immortal” hydra (second column, second row), a tiny freshwater animal that lives to be 1,400 years old. It’s just as likely to die at age 10 as it is at age 1,000:

aging hydraNature

Or the desert tortoise, which has a high rate of mortality in early life, but whose rates of mortality decline as it ages. This means that if you’re one of these critters who’s lucky enough to survive your early years, you will likely carry out your remaining (healthy) days until you reach the end.

aging tortoiseNature

What does this mean for the pursuit to ‘stop aging’?

Some scientists think we can use this knowledge to stop aging, or at least prolong life.

“Aging is not a relentless process that leads to death,” Michael Rose, an evolutionary biologist at the University of California at Irvine and the director of its Network for Experimental Research on Evolution, told Business Insider last year. (Rose didn’t work on the study above, but he has published a series of papers and books on aging and evolution.) “It’s a transitional phase of life between being amazingly healthy and stabilizing.”

Other researchers, like biologist and theoretician Aubrey de Grey, want to use our knowledge of these organisms to extend our lives. The proportion of people who die of age-related problems is high in wealthy countries, says de Grey in his recent film “The Immortalists.” “It’s absolutely clear that it’s the world’s most important problem.”

But we are not hydra or tortoises, and, for now, we can’t do away with aging. For us, aging is real, and it is long. Fortunately, many older people can still live healthy, happy lives.

“If someone’s 104, there’s not a whole lot you can do,” says Ehrlich. “But someone who’s 83? There’s plenty you can still do.”



About the author
Erin Brodwin I'm a Brooklyn-based, Los Angeles-raised science and health journalist reporting for Business Insider's Science section. My work has appeared in Business Insider, Scientific American, Popular Science, Newsweek, Psychology Today, Mic.com, and the World Science Festival. I'm also a Punch Sulzberger Scholar. I received a master's degree from the City University of New York's Graduate School of Journalism, focusing on health and science, and a bachelor's degree from the University of California, San Diego in Race and Gender Studies and Environmental Science. You can read more about me here.


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